% Derrick Roos % % make_G.m - Builds G (conductance) matrix (2nx2n). The Gij entry is the conductance from cell j to % cell i. Takes in Weight matrix W (nxn). Positive connections j to i produce a % positive G j to i. Negative connection j to i creates a weight to cell % i's inhibitory companion cell i+n, thus creating a negative weight from j % to i+n. % % G = make_G(W,g_max,g_inhib,g_EI) % where: W = Bayesian Weight Matrix % g_max = average conductance excitatory connections % g_inhib = conductance for inhibitory connections % g_EI = conductance for excitatory to inhibitory connections % output: G = Conductance Matrix, see description above for detail function G = make_G(W,g_max,g_inhib,g_EI) n = length(W); %scale E to E connections to have average strength to give 3-4 mv EPSP scale_EE = g_max/mean(W(find(W>0))); % scale E to I to have average strength to give 3-4 mv EPSP scale_EI = g_EI/mean(W(find(W<0))); thres = max(W(:))/50; G = [zeros(n,n) eye(n)*g_inhib; zeros(n,2*n)]; for i = 1:n for j = 1:n if W(i,j) > thres % connect to excitatory cell G(i,j) = W(i,j)*scale_EE; elseif W(i,j)<-thres % connect to inhibitory companion G(n+i,j) = W(i,j)*scale_EI; end end end