DATA for RC-3-10-04-B

HH GRAPHS

All of the following voltage graphs were produced by Neuron and used the built-in Hodgkin-Huxley channels (hh) and all the corresponding default properties. For the passive channel graphs look further down the page.

• gnabar_hh: The maximum specific sodium channel conductance [Default value = 0.120 S/cm2]

• gkbar_hh: The maximum specific potassium channel conductance [Default value = 0.036 S/cm2]

• gl_hh: The maximum specific leakage conductance [Default value = 0.0003 S/cm2]

• ena: The reversal potential for the sodium channel [Default value = 50 mV]

• ek: The reversal potential for the potassium channel [Default value = -77 mV]

• el_hh: The reversal potential for the leakage channel [Default value = -54.3 mV]

I ran each simulation for 300 ms (tstop = 300) with an initial voltage of -65 mV and with a stimulus located in the middle of the soma for a delay (del) of 10 ms, a duration (dur) of 10 ms, but the amplitude (amp) varied because i was to find what amplitude would cause an action potential. The axial resistance (Ra) along with the amplitude would be the only variables that i would change, i varied the Ra from 30 ohm-cm to 300 ohm-cm.

The voltage graphs for the corresponding different Ras can be found by clicking on the corresponding link below:

Ra = 30 ohm-cm

Ra = 50 ohm-cm

Ra = 75 ohm-cm

Ra = 100 ohm-cm

Ra = 150 ohm-cm

Ra = 200 ohm-cm

Ra = 300 ohm-cm

PAS GRAPHS

All of the following voltage graphs were produced also by Neuron but in these we used the built-in passive channels (pas) and the corresponding default properties that came along with it.

• g_pas: The specific membrane conductance [Default value = 0.001 S/cm2]

• e_pas: The reversal potential [Default value = -70 mV]

I ran each simulation for 300 ms (tstop = 300) with an initial voltage of -65 mV and with a stimulus located in the middle of the soma for a delay (del) of 10 ms, a duration (dur) of 10 ms, but the amplitude (amp) varied from 5,2,-2, and -5. The axial resistance (Ra) also varied from 30 to 300 ohm-cm, in the same increments as in the hh tests.

The voltage graphs for the corresponding different Ras can be found below:

Ra = 30 ohm-cm

Ra = 50 ohm-cm

Ra = 75 ohm-cm

Ra = 100 ohm-cm

Ra = 150 ohm-cm

Ra = 200 ohm-cm

Ra = 300 ohm-cm


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